A TWO-STAGE ITERATED GREEDY ALGORITHM AND A MULTI-OBJECTIVE CONSTRUCTIVE HEURISTIC FOR THE MIXED NO-IDLE FLOWSHOP SCHEDULING PROBLEM TO MINIMIZE MAKESPAN SUBJECT TO TOTAL COMPLETION TIME

A two-stage iterated greedy algorithm and a multi-objective constructive heuristic for the mixed no-idle flowshop scheduling problem to minimize makespan subject to total completion time

Advanced production systems usually are complex in nature and aim to deal with multiple performance measures simultaneously.Therefore, in most cases, the consideration of a single objective function is not sufficient to properly solve scheduling problems.This Stemware paper investigates the multi-objective mixed no-idle flowshop scheduling problem.

read more

Oral Pathobiont-Induced Changes in Gut Microbiota Aggravate the Pathology of Nonalcoholic Fatty Liver Disease in Mice

Background & AimsPeriodontitis increases the risk of nonalcoholic fatty liver disease (NAFLD); however, the underlying mechanisms are unclear.Here, we show that gut dysbiosis induced by oral administration of Porphyromonas gingivalis, a representative periodontopathic bacterium, is involved in the aggravation of NAFLD pathology.MethodsC57BL/6N

read more

Criminal punishment and early release programs

The punishment of criminals is a long-debated topic in penology, criminology, and sociology of law.But it has an underdeveloped history in philosophy Ice Cube Trays generally, and in philosophy of law in particular.Philosophical discussions of early release programs is particularly lacking in philosophy of law and moral philosophy.But in the State

read more